Welcome to DE Synthetics
DE Synthetics (DES) is a provider of synthetic and general organic chemistry support for companies and institutions engaged in research & development activities.
The core values of DE Synthetics are integrity, diligence, and respect with the goal of providing high quality and innovative synthetic support.
DES is fully owned and operated in North America in close proximity to northeastern U.S. and Canadian research centers.
The leadership of DE Synthetics has a trusted reputation from 21 years of industrial experience (12 years in pharmaceutical preclinical scale-up synthesis and 9 years in contract research). During that time a track record of delivering quality products and results has been demonstrated, including: route scouting to enable discovery chemistry efforts; synthesis of advanced intermediates for medicinal chemistry scaffold diversification; synthetic scale-up to several hundred grams of active pharmaceutical ingredients (API's) for preclinical efficacy, toxicology, pharmacokinetic, and formulation studies; process research to establish scalable syntheses in preparation for potential clinical development. This experience at the juncture of discovery and development from both sides of the pharma industry / contract research relationship has instilled valuable insights into the issues and expectations that must be met.
DES has experience with a wide range of organic chemistry including synthesis, extraction, purification, and characterization; synthesis of various heterocyclic, aromatic, acyclic, and chiral scaffolds have been accomplished, as well as studies directed towards natural product synthesis. Synthetic expertise in areas such as metal catalyzed coupling chemistry, functional group manipulations, C-C bond forming reactions, scale-up chemistry, asymmetric synthesis, substitution reactions, amide formation, halogenation, hydrogenation, etc.
Availability of in-house and local analytical support such as HPLC, NMR, mass spectrometry, FTIR, polarimetry.
The core values of DE Synthetics are integrity, diligence, and respect with the goal of providing high quality and innovative synthetic support.
DES is fully owned and operated in North America in close proximity to northeastern U.S. and Canadian research centers.
The leadership of DE Synthetics has a trusted reputation from 21 years of industrial experience (12 years in pharmaceutical preclinical scale-up synthesis and 9 years in contract research). During that time a track record of delivering quality products and results has been demonstrated, including: route scouting to enable discovery chemistry efforts; synthesis of advanced intermediates for medicinal chemistry scaffold diversification; synthetic scale-up to several hundred grams of active pharmaceutical ingredients (API's) for preclinical efficacy, toxicology, pharmacokinetic, and formulation studies; process research to establish scalable syntheses in preparation for potential clinical development. This experience at the juncture of discovery and development from both sides of the pharma industry / contract research relationship has instilled valuable insights into the issues and expectations that must be met.
DES has experience with a wide range of organic chemistry including synthesis, extraction, purification, and characterization; synthesis of various heterocyclic, aromatic, acyclic, and chiral scaffolds have been accomplished, as well as studies directed towards natural product synthesis. Synthetic expertise in areas such as metal catalyzed coupling chemistry, functional group manipulations, C-C bond forming reactions, scale-up chemistry, asymmetric synthesis, substitution reactions, amide formation, halogenation, hydrogenation, etc.
Availability of in-house and local analytical support such as HPLC, NMR, mass spectrometry, FTIR, polarimetry.